Synthesis and Characterization of Chitosan-Pectin-Citric Acid-Based Hydrogels for Biomedical Applications (Primary Wound Dressings)

This study aims to analyze the processing of chitosan-pectin biocomposite hydrogel with addition citric acid improve quality for primary wound dressing applications. The method is printing biopolymer solution in a glass mold, then drying at 50oC. Chitosan 90.2% DD and pectin dissolved 1% acetic ratio (w/w) 50:50. two ingredients were mixed using magnetic stirrer room temperature 30 minutes until completely dissolved, added crosslinking agent various concentrations 2,4, 6,8,10 (%). test results characteristics chitosan-pectin-acid Citrate obtained best thickness composition variation (50:50:8) 0.31 mm. analysis absorption chitosan-pectin-citric on (50:50:6) 185%. In swelling biocomposite, (50:50:10) was 403%. tensile strength decreased acid, 20.76 MPa, elongation 76.0%. Test functional group chitosan-pectin-CaCl2 presence O-H, C-H, N-H bonds fact wavelength 4000-2500 cm-1, C=O, C=N, C=C 2000 -1500, specific 400-1400 cm-1 indicates that resulting membrane tends be polar, hydrophilic environmentally friendly because it can degraded. Based expected results, shown has potential applied as an ideal healing protection.